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(CBS) AFI Fest 2011 runs from Nov. 3 to Nov. 10 and the film to open it will be Clint Eastwood’s latest, “J. Edgar.” The film stars Leonardo DiCaprio as the feared FBI director and features Judi Dench, Naomi Watts and Armie Hammer. Pictures: Leonardo DiCaprio The screenplay for “J. Edgar” is by Dustin Lance Black, who won the Academy Award for best original screenplay for “Milk,” Gus Van Sant’s biopic of Harvey Milk. Eastwood has won the best director Oscar twice, for “Million Dollar Baby” and “Unforgiven.” Eastwood’s last two films as director, “Hereafter” and “Invictus,” did not fare well at the box office, 해외 야구 생중계 grossing around $32 million and $37 million in their initial domestic runs, according to Box Office Mojo. “J. Edgar” opens Nov. 9 in the United States. Read more...

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nor Pakistan can afford a complete rupture in relations, Hussain said Islamabad is frustrated that the relationship has been reduced to a single point agenda: Afghanistan

ISLAMABAD — U.S. Secretary of State Mike Pompeo arrived in Pakistan on Wednesday at a time when relations between the two countries have sunk to a new low. The United States last weekend canceled a $300 million Coalition Support Fund payment to Pakistan and on board the plane to Pakistan, Pompeo announced his appointment of an unpopular figure in Pakistan, Zalmay Khalilzad, as the new U.S. special adviser on Afghan reconciliation. Pompeo said he wanted to “reset” strained relations with Pakistan, but the appointment of Khalilzad could complicate his job. “He has been very critical of Pakistan in the past and his appointment will not help move things forward,” said Zahid Hussain, defense analyst and author of two books on militancy in the region: More in Afghanistan: The way forward Khalilzad was born in Afghanistan and served as U.S. special envoy to the country following the collapse of the Taliban from 2001-2003 and then U.S. ambassador to Afghanistan from 2003-2005. He has been critical of Pakistan, often blaming the country’s deteriorating security and country-wide chaos on Pakistan’s military and powerful ISI intelligence agency, accusing them of harboring and aiding Taliban insurgents. During his visit to Pakistan, expected to last only a few hours, Pompeo was to hold meetings with new Pakistan Prime Minister Imran Khan as well as the country’s powerful army chief Qamar Javed Bajwa and Foreign Minister...

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Actress Blythe Danner — Gwyneth Paltrow’s mother — was recently diagnosed with postmenopausal osteoporosis

Osteoporosis is a disease that, over time, weakens the bones, making them more likely to break. Actress Blythe Danner — Gwyneth Paltrow’s mother — was recently diagnosed with postmenopausal osteoporosis. CBS News Medical Correspondent Dr. Jennifer Ashton sat down with the Hollywood veteran to talk about the diagnosis and how it has changed her life. For the actress, activist, mother, and grandmother, slowing down is not an option. A bone fracture can be a life changing event, as Danner learned. More on Blythe’s osteoporosis awareness campaign “When I heard the statistics that one-in-two women over the age of 50 will have a fracture related to osteoporosis, I really sat up and said, ‘This is horrific. This is more than nine million women,”‘ Danner said. Ashton said, “OK, so go back to 2009 when you broke your foot. When someone is as active and busy as you are, working woman, grandmother, and all of a sudden, you have an injury. What was that like for you?” “Terrifying,” Danner said. “I’ve been really proud of my independence.” Nearly 10 years ago, Danner’s husband of 33 years, director Bruce Paltrow lost his battle with oral cancer. Danner said, “My husband was really the heart and strength of my family, he was extraordinary,and I really had to learn how to do it all on my own. But I thought, ‘How am I going...

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Insys execs guilty of bribing doctors to push drugs, marking first U.S. conviction in opioids fight

For the first time ever, U.S. attorneys say they have successfully prosecuted a top pharmaceutical executive in the government’s fight against opioids. A federal jury on Thursday convicted Insys Therapeutics founder John Kapoor and four other former executives of the company. Prosecutors accused them of bribing doctors to prescribe a highly addictive fentanyl spray – called Subsys. One-time billionaire Kapoor was once one of the country’s biggest pharmaceutical executives. Thursday’s verdict is a sign of the government’s mounting efforts to hold drugmakers and distributors accountable for the nationwide opioid crisis. Among the pieces of evidence presented during the 10-week trial: a five-minute video promoting the fentanyl spray Subsys, featuring an Insys company salesman rapping about prescribing higher drug doses using a process known as “titration.” Prosecutors say the video was just one of the dubious tactics Insys used to boost profits which also included bribing doctors by paying them for sham speaking engagements. In 2017, CBS News learned Insys made 18,000 payments to doctors in 2016 totaling more than $2 million. Michael Canty, a former federal prosecutor who has advised states on suing opioid companies, said the prosecution’s case had “very good evidence.” “I think that this will send a message to other prosecutors that, look, these are cases that can be brought. If you have the evidence and you can put it before a jury, there’s hope you...

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