Mes: agosto 2019

Finding the right target to kill solid tumors but not healthy organ tissue will be even more complicated

Ken Shefveland’s body was swollen with cancer, treatment after treatment failing until doctors gambled on a radical approach: They removed some of his immune cells, engineered them into cancer assassins and unleashed them into his bloodstream. Immune therapy is the hottest trend in cancer care and this is its next frontier — creating “living drugs” that grow inside the body into an army that seeks and destroys tumors. Looking in the mirror, Shefveland saw “the cancer was just melting away.” A month later doctors at the Fred Hutchinson Cancer Research Center couldn’t find any signs of lymphoma in the Vancouver, Washington, man’s body. “Today I find out I’m in full remission — how wonderful is that?” said Shefveland with a wide grin, giving his physician a quick embrace. This experimental therapy marks an entirely new way to treat cancer — if scientists can make it work, safely. Early-stage studies are stirring hope as one-time infusions of supercharged immune cells help a remarkable number of patients with intractable leukemia or lymphoma. “It shows the unbelievable power of your immune system,” said Dr. David Maloney, Fred Hutch’s medical director for cellular immunotherapy who treated Shefveland with a type called CAR-T cells. “We’re talking, really, patients who have no other options, and we’re seeing tumors and leukemias disappear over weeks,” added immunotherapy scientific director Dr. Stanley Riddell. But, “there’s still lots to learn.” T cells...

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A no-fly zone is a militarily enforced area in which outside nations would prohibit Syrian warplanes from flying and attacking its own people

(AP) WASHINGTON – Iran is playing a growing role supporting the Syrian regime and is helping to build and train a militia to fight opposition forces, U.S. defense officials said Tuesday. Army Gen. Martin Dempsey, chairman of the Joint Chiefs of Staff, told Pentagon reporters that the militia, which is generally made up of Syrian Shiite forces, is being used to take the pressure off the Syrian regime forces, which have been at war for almost 18 months. “Any army would be taxed with that kind of pace,” Dempsey said. “They are having re-supply problems, they are having morale problems, they are having the kind of wear-and-tear that would come of being in a fight for as long as they have.” Dempsey also said that it appears Syrian rebels were able to shoot down a Syrian warplane, but said he has seen no indication that they are armed with heavy weapons or surface-to-air missiles, at least not yet. He says the MiG fighter could have been shot down with small arms fire. Syria has blamed the crash on a technical malfunction, but Dempsey said the cause “didn’t appear to be mechanical.” U.S. lifts sanctions on ex-Syria PMDefected PM says Assad regime on “verge of collapse”Panetta: Syria no-fly-zone “not on the front burner”Iran: “Retired” elite soldiers among 48 hostages held by Syria rebels Dempsey and Defense Secretary Leon Panetta voiced...

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Romney keeps up strong rhetoric on Russia “We’ll work with whichever president is elected by the American people

(AP) MOSCOW — President Vladimir Putin says Russia can work with Mitt Romney if he’s elected U.S. president, even though Romney has called Russia the United States’ “No. 1 geopolitical foe.” In an interview broadcast Thursday by the Kremlin-funded Russia Today TV channel, Putin made his first direct comments about the Republican challenger to President Barack Obama. Romney keeps up strong rhetoric on Russia “We’ll work with whichever president is elected by the American people. But our effort will be only as efficient as our partners will want it to be,” Putin said. Putin expressed concern about how a Romney presidency would affect the long-running dispute over U.S.-led NATO plans to place elements of a missile-defense system in Europe. Russia contends the system could undermine its own defenses. Putin said if Romney is elected “the missile defense system will definitely be directed against Russia.” The wide-ranging interview showed Putin’s acerbic and combative side, particularly on the issue of the two-year prison sentence imposed last month on three members of the provocateur band Pussy Riot for their “punk prayer” prank in Moscow’s main cathedral entreating the Virgin Mary to save Russia from Putin. Their conviction brought widespread criticism of Russia for stifling opposition and free speech. Putin briefly sparred with the English-speaking interviewer over how the band’s name could be translated into Russian, 맞고사이트 saying “I think you wouldn’t do...

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Interviews With Four Convicted Sexual Predators –

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